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- Creative Biostructure Upgrades Liposome Service to Enable Tailored Drug Delivery SolutionsAmid the swift progress in global drug delivery innovations, Creative Biostructure, a top-tier service provider in structural biology and nanomedicine, revealed today an extensive upgrade to its liposome service. This enhancement is set to deliver more nuanced and tailored liposome production services for corporate clients, addressing needs from early-stage research to clinical application...0 Commentarii 0 Distribuiri 3563 Views
- How are Liposomes Different from Micelles?What are Liposomes? Liposome is an artificial carrier membrane. In the water, the hydrophilic head of the phospholipid molecule is inserted into the water, and the hydrophobic tail of the liposome extends to the air, and after agitation, a spherical liposome of bilayer lipid molecules is formed. This bilayer structure is the same as the skin cell membrane structure, which helps the skin to...0 Commentarii 0 Distribuiri 2084 Views
- How CROs and Biotech Firms Use Pomalidomide Derivatives for Rapid PROTAC ScreeningContract research organizations and boutique biotech groups have developed pomalidomide derivatives into the most widely used plug-and-play CRBN recruiters: the scaffold provides a clean departure point, gram-scale commercial availability and a largely 'greyed' intellectual-property landscape. Stocking a freezer full of pre-functionalized C4- and C5-linker congeners (acetamides,...0 Commentarii 0 Distribuiri 2183 Views
- Peptide Vaccine Challenges: How to Enhance Stability and Efficacy?In the field of vaccine development, peptide vaccines, as an emerging vaccine platform, have gradually become the focus of research due to their advantages such as high safety, strong targeting, and customizability. However, despite the great potential shown by peptide vaccines, stability and immunogenicity remain two major challenges in their application process. Issues such as peptide...0 Commentarii 0 Distribuiri 1050 Views
- The Development Process of DUBTACThe use of Proteolysis Targeting Chimeras (PROTACs) to degrade dysfunctional proteins has shown great potential to target proteins that were previously considered "undruggable", and several projects have entered clinical evaluation worldwide. Aberrant protein degradation, in fact, is also a pathogenic mechanism in some diseases, such as cystic fibrosis (CF) and some forms of cancer....0 Commentarii 0 Distribuiri 2017 Views
- What is Transcriptomics?Transcriptomics Definition Transcriptomics is the study of the overall expression of all transcribed RNAs (mRNAs, non-coding RNAs including siRNAs, miRNAs, lincRNAs, etc.) and their regulation in living organisms. It comprehensively analyzes and identifies transcripts in cells or tissues through high-throughput sequencing technology, and quantitatively and functionally analyzes them through...0 Commentarii 0 Distribuiri 1018 Views