The in vitro micronucleus (MNvit) test is a genotoxicity assay that detects micronuclei in the cytoplasm of interphase cells. Micronuclei can originate from acentric chromosome fragments (i.e. fragments lacking centromeres) or entire chromosomes that fail to migrate to the cell poles during metaphase. The assay quantifies the clastogenic and chromosomal aberration-inducing activity of test...
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